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Wasn't D. Afonso the 7th child and 5th son of King Manuel?
Infante D.Afonso of Portugal, 6th child and 4th son of king D.Manuel was assigned by his father to the religious life with the chair of Saint Peter in the sight.
He was born in April, 23.1509.
When he was 3, his father asked the Pope to make him a cardinal, but the Pope refused on age ground.
At the age of 7 he became bishop of Guarda, and at the age of 8, due to the famous embassy to the Pope, the king got him the cardinal title.
At the age of 10, he became bishop of Viseu and when he was 14, he became archbishop of Lisbon.
The same year he became archbishop of Évora too.