I can't compare the kind of drugs you need to take for pricing but I can give you my experience with my glaucoma eyedrops. I take two types, neither are generic and a MUST, one I use twice a day, the other once a day. Retail price for each is about $112/mo. There's no comparison I can make on the one a day but the other I use the most of is a combination of two other drugs both of which can be had on their own much cheaper. For the same quantity, the retail price would be about $24/mo. How much research costs would be involved in combining the two that makes this one so expensive?