The Pragmática was published before Princess Isabel was born.
And no ecographies at that time, you know.
Carlist bastards ? Because D.Carlos refused to accept the Pragmatica his brother issued when he discovered he would not father a son ?
Well, you surely know that, as soon as he grabbed the spanish throne via a female, the arrivist Bourbon Felipe
V cut any oportunity for a female to inherit the throne and, monkey sees, monkey does, he introduced in Spain the french salic law.
D.Carlos was his brother's heir until Fernando VII decided otherwise, cutting his legitimate expectations with a signature.
D.Carlos was not amused with his brother's action. Who could blame him ?
Queen Isabel II of Spain: she was only three years old when her father, King Fernando VII, died -- and her accession triggered the Carlist wars (those bastards seemed to have a hard time in remembering their history, as they conveniently forgot how the Bourbons even came to the Spanish throne in the first place -- via Infanta Maria Teresa)