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How could the world have been affected? We have no way of knowing just what kind of marriage the Prince of Wales and Princess Elisabeth of Wied would have had, or what kind of children.

We know that she was not a sterile person, since she did manage to conceive and carry a child. It's just that she wasn't a very fertile person: somehow, she was unable to get pregnant again, after the death of her only child. But this is no indication of the fertility of an hypothetical marriage between her and the future King Edward VII of Great Britain. As it was, by a twist of fate, her husband's nephew adopted an heir who married the British king's niece, Princess Marie of Edinburgh, Saxe-Coburg and Gotha ...

As for the political aspect of a union with a mediatized German house ... it's difficult to say ..,

And I know very little about the other Marie, Princess of the Netherlands. The main focus of my original post was Elisabeth, for the simple reason is that she's the only princess from a non-sovereign house I personally know of who became the queen consort of a sovereign country, since 1800.