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Very good questions! First, glad you don't need the Adriamycin YUKKKKKKK
Sometimes the chemo area can be cool, so either bring a light jacket or sweater or blanket. DEFINITELY bring several bottles of water to drink. Make sure you drink the day before chemo, the day of and the days after. I would also bring a snack(s).
My chemo day went like this: first I waited to have blood work (every time - to be sure white count is ok), then wait to see the Onc, then wait for my turn at chemo which can take up to four hours, depending on how many drugs you are taking and how fast they push them through. It can be a very long day.
Sometimes you are given benedryl which could make you sleep through the whole thing! It's given in case of an (rare) allergic reaction. I also brought crossword puzzles, or magazines/books or crochet, etc. I didn't need anyone with me, but some gals do. Many chemo patients were I was were by themselves - we got to know each other and chatted away. It made the time go by fast. You do need someone to bring you home in case you are drowzy.
Usually I was just a little flushed the first day. You will do fine. The vast majority of us don't have any problems at all other than a day or two of icky.
Don't forget to hydrate much more than you usually do. You'll be dragging the pole behind you to the potty, but that's OK.
HUGS!!!!! and FIGHT ON.