Posted by Emma on 2/26/2005, 6:28 am >>
172.129.29.2
This was posted on a list by someone who is so confused, I wouldn't trust her to tell me the correct day of the week, but I didn't find it listed on snopes.com either. It sounds so naive, e.g., "the drug is available over the counter through health food stores and is labeled "tumeric"." (Since when is tumeric a "drug" in any sense in which we use the word?)Anyway, FWIW.
**Subject: New Natural Treatment for Mast Cell Tumors
>> Note permission to forward at bottom
>>
>> ******************************************************************
>>
>> Subject: alternative treatment for cancer
>>
>> this past fall, Meeko (akc intl pr ch ukc gr ch Thundrpas Meeko
>> of Jaybar) was diagnosed with mast cell cancer. it was originally a
>> large what we hoped isolated tumor located on the back of her neck,
>> which was removed.
>> grade II (on a scale of I-III, III being metatasized) at the time,
>> highly aggressive. while we hoped for the best, the vet said it
>> would
>> be back quickly if it had metatasized.
>>
>> it had. the first week of January, Meeko began having tumors show up
>> on
>> her head, neck, muzzle, chest, back, sides, underarms -
>> dozens everywhere. there also appears to be a large hard mass under
>> her
>> front left shoulderblade.
>>
>> a long story, but I decided to try an experimental drug that
>> has shown success in treating mast cell tumors in cell culture and
>> other
>> types of cancer in mice, called curcumin. this is the yellow in
>> tumeric,
>> a spice found
>> in curry powder. this both cuts off the blood supply to the growing
>> tumor as well as causes tumor cell death (p53 mediated apoptosis).
>>
>> the dosage we started with was 80 mg/kg/day, or 400 mg twice a day
>> for a
>> 25 lb dog., administered orally. the drug is available over the
>> counter through health food stores and is labeled "tumeric".
>>
>> at 8 days, most of the tumors turned black, clotted, and
>> disappeared.
>> the large mass changed consistency. unfortunately, at 10 days it
>> was clear that some tumors had not been killed. we have now
>> increased
>> the dosage to
>> 120 mg/day, which is the highest we can go without toxicity.
>>
>> the drug has no apparent side affects - eating is good, she
>> is actually feeling much better, the limp in the front left leg is
>> gone
>> and she is again climbing stairs. we can remove the small tumors on
>> the
>> body, IF the
>> big ones are killed.....
>>
>> I will keep you posted. However, the important news is that the
>> folks
>> at Emory Medical School are planning a study to test another
>> compound, a
>> curcumin that has been modified so more is absorbed orally, in dogs
>> with
>> mast
>> cell cancer, based on the results in Meeko. this technology is
>> being developed by a small start up company called Curry
>> Pharmaceuticals.
>>
>> anyone interested should contact Dr. Jack Arbiser at Emory (I
>> will forward contact information directly for those interested).
>>
>> PLEASE SHARE WITH ALL DOG EMAIL LISTS! YOU MAY SAVE A LIFE.
>>
>> Anne
>> Dr. Camelia Anne Bishop
>> www.myamericaneskimodogs.com**
>
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